{"id":1825,"date":"2025-09-01T09:45:02","date_gmt":"2025-09-01T07:45:02","guid":{"rendered":"https:\/\/www.cystinose-stiftung.de\/aktuelles\/new-evidence-on-cystinosis-foundation-for-the-select-s3-guideline\/"},"modified":"2025-09-01T09:45:02","modified_gmt":"2025-09-01T07:45:02","slug":"new-evidence-on-cystinosis-foundation-for-the-select-s3-guideline","status":"publish","type":"post","link":"https:\/\/www.cystinose-stiftung.de\/en\/aktuelles\/new-evidence-on-cystinosis-foundation-for-the-select-s3-guideline\/","title":{"rendered":"New evidence on cystinosis \u2013 foundation for the SELECT-S3 guideline"},"content":{"rendered":"<p>Cystinosis is a rare disorder with severe consequences if not diagnosed and treated early. A new article in the <em>Orphanet Journal of Rare Diseases<\/em> systematically reviews the current evidence on diagnosis and management.<\/p>\n<p>Analysis of 56 studies revealed:<\/p>\n<ul>\n<li>Only a few questions are backed by robust evidence<\/li>\n<li>Most results are based on very low certainty<\/li>\n<li>Early cysteamine therapy benefits kidney function<\/li>\n<li>Delayed-release formulations show no clear advantage<\/li>\n<\/ul>\n<p>The findings highlight the urgent need for stronger research \u2013 and provide the evidence base for the new <strong>SELECT-S3 guideline on cystinosis<\/strong>.<\/p>\n<p>Read the publication: <a rel=\"nofollow\"  href=\"https:\/\/ojrd.biomedcentral.com\/articles\/10.1186\/s13023-025-03974-z?utm_source=chatgpt.com\">Link<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cystinosis is a rare disorder with severe consequences if not diagnosed and treated early. A new article in the Orphanet Journal of Rare Diseases systematically reviews the current evidence on diagnosis and management. Analysis of 56 studies revealed: Only a few questions are backed by robust evidence Most results are based on very low certainty [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":1823,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[5],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/www.cystinose-stiftung.de\/en\/wp-json\/wp\/v2\/posts\/1825"}],"collection":[{"href":"https:\/\/www.cystinose-stiftung.de\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.cystinose-stiftung.de\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.cystinose-stiftung.de\/en\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.cystinose-stiftung.de\/en\/wp-json\/wp\/v2\/comments?post=1825"}],"version-history":[{"count":0,"href":"https:\/\/www.cystinose-stiftung.de\/en\/wp-json\/wp\/v2\/posts\/1825\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.cystinose-stiftung.de\/en\/wp-json\/wp\/v2\/media\/1823"}],"wp:attachment":[{"href":"https:\/\/www.cystinose-stiftung.de\/en\/wp-json\/wp\/v2\/media?parent=1825"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.cystinose-stiftung.de\/en\/wp-json\/wp\/v2\/categories?post=1825"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.cystinose-stiftung.de\/en\/wp-json\/wp\/v2\/tags?post=1825"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}